Cannon continues biotechnology, life sciences seminar series

Judy Cannon
Judy Cannon

"T Cell Movement During the Immune Response and Leukemia," will be presented by Judy Cannon of the University of New Mexico Health Sciences Center at 4 p.m., Feb. 18 in E103 Beadle Center. The seminar is free and open to the public.

Movement of T cells is crucial for every phase of T cell function from the initiation of the immune response to effector function at sites of inflammation. While T cell motility is critical to immune function, relatively little is known about the fundamental mechanisms that drive how T cells move. Cannon's laboratory is focused on understanding the fundamental mechanisms that control T cell movement in tissues including lymph nodes and the lung. Using a combination of cutting edge in vivo two-photon imaging and computational modeling, her lab quantitatively defines how T cells move in tissues.

Cannon's lab developed sophisticated computational analysis and modeling tools to determine how T cells search for targets in tissues. Researchers are also studying the migration of leukemic cells of T cell origin in T-acute lymphoblastic leukemia (T-ALL) to the central nervous system. Understanding the mechanisms that regulate T cell movement can provide insight into a fundamental T cell function and may lead to novel therapeutic targets to modulate the immune response and disease states.

The Beadle Center is located at 1901 Vine Street. The complete schedule of seminars may be found at http://biotech.unl.edu/.

More details at: http://go.unl.edu/u79i