In his lecture titled Large-scale logical models and emergent dynamics of biochemical and biological networks under healthy and diseased conditions, Dr. Helikar, according to his abstract, will discuss qualitative computational frameworks, especially those based on the logical discrete formalism, and how they are widely used to model biochemical and biological networks. Also discussed will be examples of some of the largest logical models created to study various diseases, including HIV, breast cancer and influenza. Dr. Helikar will share various software technologies developed to provide new tools to build, simulate and analyze large-scale logical models, as well as sharing these models via a new extension of the Systems Biology Mark-up Language (SBML). In conclusion, Dr. Helikar will explore new opportunities for innovation in the area of STEM education in life sciences through the use of interactive computation modeling.
Dr. Tomas Helikar is an Assistant Professor in the Department of Biochemistry at UNL. His research expertise is in computational systems biology, technology development, and STEM education.
The CSE Colloquium Series is funded in part by donations from the Union Pacific Corporation.