Peng to talk at biotechnology seminar Feb. 22

Dr. Aimin Peng
Dr. Aimin Peng

“DNA damage checkpoint recovery and cancer,” will be presented by Dr. Aimin Peng, University of Nebraska Medical Center. The seminar begins at 4 p.m., Feb. 22, preceded by a reception at 3:30 p.m. The seminar is free and open to the public at the Beadle Center.

The DNA damage response is a cellular surveillance mechanism that protects genomic integrity and prevents tumorigenesis. The DDR pathway also determines the outcome of cancer treatment, especially radiation and chemotherapy using genotoxic agents. The long-term goal of Peng's research is to investigate how the DDR fails in cancer cells to prevent genomic instability and uncontrolled cell proliferation, and to understand how some cancer cells develop resistance to genotoxic drugs.

"Our research efforts are focused on the poorly-understood turn-off mechanism of the DDR, termed "checkpoint recovery," which process may hold a key to understanding how tumor cells escape the DDR in both cancer progression and chemotherapy.

The complete schedule of seminars may be found at

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