M.S. Thesis Defense: Ankitha Vejandla
Wednesday, September 29, 2021
11:00 AM (CST)
Zoom: https://unl.zoom.us/j/94762821070
"Comparative Analysis Of K-mer Counting And Estimation Tools"
The rapid development of next-generation sequencing (NGS) technologies for determining the sequence of DNA has revolutionized genome research in recent years. De novo assemblers are the most commonly used tools to perform genome assembly. Most of the assemblers use de Bruijn graphs that break the sequenced reads into smaller sequences (sub-strings), called k-mers, where k denotes the length of the sub strings. The kmer counting and analysis of kmer frequency distribution are important in genome assembly. The main goal of this research is to provide a detailed analysis of the performance of different kmer counting and estimation tools that are currently available. This helps the bioinformatics researchers to make a good decision in choosing accurate and efficient tools for genome assemblers.
Committee:
Dr. Jitender Deogun, Chair
Dr. Vinod Variyam
Dr. Etsuko Moriyama