"Mechanical Disassembly and Reassembly of Reproduction in Mammals," will be presented by Oliver Rando of the University of Massachusetts Medical School at 4 p.m., Dec. 2 in E103 Beadle Center. The seminar is free and open to the public.
It is increasingly clear that ancestral environmental conditions can influence the phenotype of future generations. Rando and others have linked paternal dietary exposures to metabolic phenotypes in offspring, with key metabolic consequences being alterations in glucose control and cholesterol metabolism.
Using in vitro fertilization, Rando has now demonstrated that paternal dietary information is carried by sperm rather than seminal fluid or other information carriers. Rando will discuss our latest results on dietary control of the sperm epigenome during testicular and post-testicular maturation, and on the effects of paternal diet on gene regulation in the preimplantation embryo.
The Beadle Center is located at 1901 Vine Street. The complete schedule of seminars may be found at http://biotech.unl.edu/.
More details at: http://go.unl.edu/tomp